Basal Patologi KU - BAD, BID and PUMA proteins shift the balance between the pro-apoptotic and anti-apoptotic family members by neutralizing the actions of anti-apoptotic proteins like BCL2 and BCL-XL, thereby promoting
![a) Linear representation of the PUMA protein with each tyrosine, the... | Download Scientific Diagram a) Linear representation of the PUMA protein with each tyrosine, the... | Download Scientific Diagram](https://www.researchgate.net/profile/Hui-Wen-Lo-2/publication/258530917/figure/fig3/AS:214001737834499@1428033398515/a-Linear-representation-of-the-PUMA-protein-with-each-tyrosine-the-BH3-domain-and.png)
a) Linear representation of the PUMA protein with each tyrosine, the... | Download Scientific Diagram
![Inhibiting aberrant p53-PUMA feedback loop activation attenuates ischaemia reperfusion-induced neuroapoptosis and neuroinflammation in rats by downregulating caspase 3 and the NF-κB cytokine pathway | Journal of Neuroinflammation | Full Text Inhibiting aberrant p53-PUMA feedback loop activation attenuates ischaemia reperfusion-induced neuroapoptosis and neuroinflammation in rats by downregulating caspase 3 and the NF-κB cytokine pathway | Journal of Neuroinflammation | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12974-018-1271-9/MediaObjects/12974_2018_1271_Fig6_HTML.png)
Inhibiting aberrant p53-PUMA feedback loop activation attenuates ischaemia reperfusion-induced neuroapoptosis and neuroinflammation in rats by downregulating caspase 3 and the NF-κB cytokine pathway | Journal of Neuroinflammation | Full Text
![Inhibiting aberrant p53-PUMA feedback loop activation attenuates ischaemia reperfusion-induced neuroapoptosis and neuroinflammation in rats by downregulating caspase 3 and the NF-κB cytokine pathway | Journal of Neuroinflammation | Full Text Inhibiting aberrant p53-PUMA feedback loop activation attenuates ischaemia reperfusion-induced neuroapoptosis and neuroinflammation in rats by downregulating caspase 3 and the NF-κB cytokine pathway | Journal of Neuroinflammation | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12974-018-1271-9/MediaObjects/12974_2018_1271_Fig4_HTML.png)
Inhibiting aberrant p53-PUMA feedback loop activation attenuates ischaemia reperfusion-induced neuroapoptosis and neuroinflammation in rats by downregulating caspase 3 and the NF-κB cytokine pathway | Journal of Neuroinflammation | Full Text
![A review of the role of Puma, Noxa and Bim in the tumorigenesis, therapy and drug resistance of chronic lymphocytic leukemia | Cancer Gene Therapy A review of the role of Puma, Noxa and Bim in the tumorigenesis, therapy and drug resistance of chronic lymphocytic leukemia | Cancer Gene Therapy](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fcgt.2012.84/MediaObjects/41417_2013_Article_BFcgt201284_Fig1_HTML.jpg)
A review of the role of Puma, Noxa and Bim in the tumorigenesis, therapy and drug resistance of chronic lymphocytic leukemia | Cancer Gene Therapy
![A model for PUMA-mediated apoptosis. PUMA activates Bax/Bak indirectly... | Download Scientific Diagram A model for PUMA-mediated apoptosis. PUMA activates Bax/Bak indirectly... | Download Scientific Diagram](https://www.researchgate.net/profile/Lin-Zhang-2/publication/26704262/figure/fig1/AS:281230575718419@1444062002476/A-model-for-PUMA-mediated-apoptosis-PUMA-activates-Bax-Bak-indirectly-by-relieving-the.png)
A model for PUMA-mediated apoptosis. PUMA activates Bax/Bak indirectly... | Download Scientific Diagram
BH3-only sensors Bad, Noxa and Puma are Key Regulators of Tacaribe virus-induced Apoptosis | PLOS Pathogens
![Slug mediates nasopharyngeal carcinoma radioresistance via downregulation of PUMA in a p53-dependent and -independent manner Slug mediates nasopharyngeal carcinoma radioresistance via downregulation of PUMA in a p53-dependent and -independent manner](https://www.spandidos-publications.com/article_images/or/33/5/OR-33-05-2631-g03.jpg)
Slug mediates nasopharyngeal carcinoma radioresistance via downregulation of PUMA in a p53-dependent and -independent manner
BITC treatment increases PUMA protein level in MCF-7 and MDA-MB-231... | Download Scientific Diagram
![Chloroquine promotes apoptosis in melanoma cells by inhibiting BH3 domain-mediated PUMA degradation. - Abstract - Europe PMC Chloroquine promotes apoptosis in melanoma cells by inhibiting BH3 domain-mediated PUMA degradation. - Abstract - Europe PMC](https://europepmc.org/articles/PMC3675185/bin/nihms439867f5.jpg)
Chloroquine promotes apoptosis in melanoma cells by inhibiting BH3 domain-mediated PUMA degradation. - Abstract - Europe PMC
![Recombinant Human BCL2 binding component 3 (PUMA), transfected HEK293 cell culture supernatant Protein [230-20081-200] Recombinant Human BCL2 binding component 3 (PUMA), transfected HEK293 cell culture supernatant Protein [230-20081-200]](http://www.raybiotech.com/images/detailed/63/Protein_button.gif)
Recombinant Human BCL2 binding component 3 (PUMA), transfected HEK293 cell culture supernatant Protein [230-20081-200]
![Evaluation of the BH3-only Protein Puma as a Direct Bak Activator* - Journal of Biological Chemistry Evaluation of the BH3-only Protein Puma as a Direct Bak Activator* - Journal of Biological Chemistry](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/284ea938-6222-4f09-bb76-027e56f38276/gr1.jpg)
Evaluation of the BH3-only Protein Puma as a Direct Bak Activator* - Journal of Biological Chemistry
![Multimodal Interaction with BCL-2 Family Proteins Underlies the Proapoptotic Activity of PUMA BH3 - ScienceDirect Multimodal Interaction with BCL-2 Family Proteins Underlies the Proapoptotic Activity of PUMA BH3 - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S1074552113002408-fx1.jpg)